Antimicrobial treatment of ENT infections

•Ear, nose and throat (ENT) are the most common infections in children and the leading causes of antibiotic prescriptions.•Management is based on rapid diagnostic tests for group A streptococcus (GAS).•The GAS rapid antigen test could be useful for other ENT infections.•Amoxicillin is the first-line treatment in most cases of ambulatory ENT justifying antibiotics.•Severe ENT infections (mastoiditis, epiglottitis, retro- and parapharyngeal abscesses, ethmoiditis) are therapeutic emergencies necessitating hospitalization and initial intravenous antibiotic therapy.