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The protective effect of taurine against gentamicin-induced acute tubular necrosis in rats.

Authors :
Erdem, A
Gündoğan, N U
Usubütün, A
Kilinç, K
Erdem, S R
Kara, A
Bozkurt, A
Source :
Nephrology Dialysis Transplantation; August 2000, Vol. 15 Issue: 8 p1175-1182, 8p
Publication Year :
2000

Abstract

Taurine, which is the major intracellular free beta-amino acid, is known to be an endogenous antioxidant and a membrane-stabilizing agent. In this study, we wished to know whether taurine altered the concentration of gentamicin in kidney tissue and could protect against gentamicin-induced acute proximal tubular injury.

Details

Language :
English
ISSN :
09310509 and 14602385
Volume :
15
Issue :
8
Database :
Supplemental Index
Journal :
Nephrology Dialysis Transplantation
Publication Type :
Periodical
Accession number :
ejs63995637
Full Text :
https://doi.org/10.1093/ndt/15.8.1175