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Characterization of a DNA binding site that mediates the stimulatory effect of cyclosporin-A on type III collagen expression in renal cells.
- Source :
- Nephrology Dialysis Transplantation; June 2000, Vol. 15 Issue: 6 p778-785, 8p
- Publication Year :
- 2000
-
Abstract
- Previous work from our laboratory demonstrated upregulation of type III collagen by cyclosporin A (CsA) in a cellular model of renal fibroblasts 'in vitro', suggesting that a mechanism of gene transcriptional activation might be responsible for collagen accumulation in renal fibrosis resulting from chronic CsA treatment.
Details
- Language :
- English
- ISSN :
- 09310509 and 14602385
- Volume :
- 15
- Issue :
- 6
- Database :
- Supplemental Index
- Journal :
- Nephrology Dialysis Transplantation
- Publication Type :
- Periodical
- Accession number :
- ejs63995555
- Full Text :
- https://doi.org/10.1093/ndt/15.6.778