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Cyclosporin inhibits nitric oxide production in medullary ascending limb cultured cells.
- Source :
- Nephrology Dialysis Transplantation; November 1998, Vol. 13 Issue: 11 p2814-2820, 7p
- Publication Year :
- 1998
-
Abstract
- Nitric oxide (NO) has been shown to play a role in cyclosporin (CsA) nephrotoxicity, but its mechanism of action is still unclear. As inducible NO synthase (iNOS) mRNA has been found to be expressed in rat medullary thick ascending limb (mTAL) cells, we investigated the effects of CsA on NO production in a model of mouse cultured mTAL cells.
Details
- Language :
- English
- ISSN :
- 09310509 and 14602385
- Volume :
- 13
- Issue :
- 11
- Database :
- Supplemental Index
- Journal :
- Nephrology Dialysis Transplantation
- Publication Type :
- Periodical
- Accession number :
- ejs63995442
- Full Text :
- https://doi.org/10.1093/oxfordjournals.ndt.a027801