Mycophenolic acid plasma concentrations in kidney allograft recipients with or without cyclosporin: a cross-sectional study.

Authors :: Smak Gregoor, P J
van Gelder, T
Hesse, C J
van der Mast, B J
van Besouw, N M
Weimar, W
Source :: Nephrology Dialysis Transplantation; March 1999, Vol. 14 Issue: 3 p706-708, 3p
Publication Year :: 1999
Abstract: Combining cyclosporin (CsA) and prednisone with mycophenolate mofetil (MMF) results in a significant reduction in the rate of biopsy-proven acute rejection after kidney transplantation. This is achieved with a standard daily MMF dosage of 2 or 3 g. Whether monitoring of the pharmacologically active metabolite mycophenolic acid (MPA) will lead to improved safety and efficacy is unclear.

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