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Changes in leukoencephalopathy and serum neurofilament after (neo)adjuvant chemotherapy for breast cancer

Authors :
Schroyen, Gwen
Sleurs, Charlotte
Ottenbourgs, Tine
Leenaerts, Nicolas
Nevelsteen, Ines
Melis, Michelle
Smeets, Ann
Deprez, Sabine
Sunaert, Stefan
Source :
Translational Oncology; November 2023, Vol. 37 Issue: 1
Publication Year :
2023

Abstract

•Persistent increased white matter lesion volume after chemotherapy for breast cancer.•Serum NfL, an axonal damage marker, levels followed the chemotherapy trajectory.•Serum NfL levels were associated with lesions one-year post-chemotherapy.•Potential of NfL to support therapeutic decision, disease activity or treatment response.

Details

Language :
English
ISSN :
19447124 and 19365233
Volume :
37
Issue :
1
Database :
Supplemental Index
Journal :
Translational Oncology
Publication Type :
Periodical
Accession number :
ejs63973081
Full Text :
https://doi.org/10.1016/j.tranon.2023.101769