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Practice change: No benefit of extended lymphadenectomy at radical cystectomy in patients with muscle invasive bladder cancer
- Source :
- Seminars in Oncology; June-October 2023, Vol. 50 Issue: 3-5 p102-104, 3p
- Publication Year :
- 2023
-
Abstract
- For many decades, extended pelvic lymph node dissection has been an integral part during radical cystectomy for patients with muscle invasive bladder cancer. This practice was based on large retrospective meta-analyses suggesting an oncologic benefit to an extended dissection. This mini review and meta-analysis includes the two available randomized trials in the current literature. Therefore, it can be considered as the strongest level of evidence regarding the prognostic benefit of an extended pelvic lymphadenectomy. Based on current randomized data, standard pelvic lymph node dissection up to the level of iliac bifurcation is sufficient, and extension of the dissection above this level does not provide any additional oncologic benefit.
Details
- Language :
- English
- ISSN :
- 00937754 and 15328708
- Volume :
- 50
- Issue :
- 3-5
- Database :
- Supplemental Index
- Journal :
- Seminars in Oncology
- Publication Type :
- Periodical
- Accession number :
- ejs63963317
- Full Text :
- https://doi.org/10.1053/j.seminoncol.2023.09.001