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Targeted therapy with nanatinostat and valganciclovir in recurrent EBV-positive lymphoid malignancies: a phase 1b/2 study

Authors :
Haverkos, Bradley
Alpdogan, Onder
Baiocchi, Robert
Brammer, Jonathan E.
Feldman, Tatyana A.
Capra, Marcelo
Brem, Elizabeth A.
Nair, Santosh
Scheinberg, Phillip
Pereira, Juliana
Shune, Leyla
Joffe, Erel
Young, Patricia
Spruill, Susan
Katkov, Afton
McRae, Robert
Royston, Ivor
Faller, Douglas V.
Rojkjaer, Lisa
Porcu, Pierluigi
Source :
Blood Advances; October 2023, Vol. 7 Issue: 20 p6339-6350, 12p
Publication Year :
2023

Abstract

•Nanatinostat plus valganciclovir is a novel oral regimen for relapsed/refractory EBV+lymphoma that warrants further investigation.•Encouraging efficacy and safety were observed across a variety of EBV+lymphoma subtypes.

Details

Language :
English
ISSN :
24739529 and 24739537
Volume :
7
Issue :
20
Database :
Supplemental Index
Journal :
Blood Advances
Publication Type :
Periodical
Accession number :
ejs63694798
Full Text :
https://doi.org/10.1182/bloodadvances.2023010330