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Azathioprine and 6-mercaptopurine-induced intrahepatic cholestasis of pregnancy: Case report and review of the literature

Authors :
Wolf, Maya Frank
Sloma, Ronen
Akria, Luiza
Rimon, Eli
Wiener, Yifat
Haggai, Michal Carmiel
Lowenstein, Lior
Source :
Taiwanese Journal of Obstetrics and Gynecology; 20230101, Issue: Preprints
Publication Year :
2023

Abstract

Azathioprine, a prodrug of 6-mercaptopurine (6-MP), is used in the treatment of inflammatory bowel disease and may be continued during pregnancy. Acute cholestatic liver injury has been reported to occur with azathioprine. We aimed to examine azathioprine related cholestasis effect on pregnancy complications and outcome.

Details

Language :
English
ISSN :
10284559
Issue :
Preprints
Database :
Supplemental Index
Journal :
Taiwanese Journal of Obstetrics and Gynecology
Publication Type :
Periodical
Accession number :
ejs63533915
Full Text :
https://doi.org/10.1016/j.tjog.2023.07.023