Comparison of the clinical accuracy of Xpert HPV on vaginal self- and cervical clinician-taken samples within the VALHUDES framework

The accuracy of hrHPV testing with the Xpert HPV assay on vaginal self-samples was compared with clinician-taken samples within the VALHUDES framework. We recruited 523 women in five Belgian colposcopy clinics, of which 483 (median age 40 years; IQR 31-49) were included in the main analysis (226 collected with Evalyn Brush and 257 with Qvintip). Cervical samples were collected with Cervex-Brush. Colposcopy and histology outcomes were considered as the reference standard.