Back to Search Start Over

Structural connectivity mediates the relationship between blood oxygenation and cognitive function in sickle cell anemia

Authors :
Clayden, Jonathan D.
Stotesbury, Hanne
Kawadler, Jamie M.
Slee, April
Kӧlbel, Melanie
Saunders, Dawn E.
Hood, Anna M.
Wilkey, Olu
Layton, Mark
Inusa, Baba
Pelidis, Maria
Chakravorty, Subarna
Rees, David C.
Howard, Jo
Awogbade, Moji
Liossi, Christina
Kirkham, Fenella J.
Clark, Chris A.
Source :
Blood Advances; June 2023, Vol. 7 Issue: 11 p2297-2308, 12p
Publication Year :
2023

Abstract

•Patients with sickle cell disease have weakened brain white matter connectivity compared with control subjects.•Weakened connectivity mediates the relationship between oxygen saturation and processing speed in patients.

Details

Language :
English
ISSN :
24739529 and 24739537
Volume :
7
Issue :
11
Database :
Supplemental Index
Journal :
Blood Advances
Publication Type :
Periodical
Accession number :
ejs63033792
Full Text :
https://doi.org/10.1182/bloodadvances.2021006751