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Biallelic truncating variants in MAPKAPK5cause a new developmental disorder involving neurological, cardiac, and facial anomalies combined with synpolydactyly

Authors :
Horn, Denise
Fernández-Núñez, Elisa
Gomez-Carmona, Ricardo
Rivera-Barahona, Ana
Nevado, Julian
Schwartzmann, Sarina
Ehmke, Nadja
Lapunzina, Pablo
Otaify, Ghada A.
Temtamy, Samia
Aglan, Mona
Boschann, Felix
Ruiz-Perez, Victor L.
Source :
Genetics in Medicine; April 2021, Vol. 23 Issue: 4 p679-688, 10p
Publication Year :
2021

Abstract

This study aimed to identify the genetic cause of a new multiple congenital anomalies syndrome observed in three individuals from two unrelated families.

Details

Language :
English
ISSN :
10983600 and 15300366
Volume :
23
Issue :
4
Database :
Supplemental Index
Journal :
Genetics in Medicine
Publication Type :
Periodical
Accession number :
ejs63009256
Full Text :
https://doi.org/10.1038/s41436-020-01052-2