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Spatial Correspondence of LSD-Induced Variations on Brain Functioning at Rest With Serotonin Receptor Expression

Authors :
Delli Pizzi, Stefano
Chiacchiaretta, Piero
Sestieri, Carlo
Ferretti, Antonio
Onofrj, Marco
Della Penna, Stefania
Roseman, Leor
Timmermann, Christopher
Nutt, David J.
Carhart-Harris, Robin L.
Sensi, Stefano L.
Source :
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging; July 2023, Vol. 8 Issue: 7 p768-776, 9p
Publication Year :
2023

Abstract

Lysergic acid diethylamide (LSD) is an atypical psychedelic compound that exerts its effects through pleiotropic actions, mainly involving 1A/2A serotoninergic (5-HT) receptor subtypes. However, the mechanisms by which LSD promotes a reorganization of the brain’s functional activity and connectivity are still partially unknown.

Details

Language :
English
ISSN :
24519022
Volume :
8
Issue :
7
Database :
Supplemental Index
Journal :
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
Publication Type :
Periodical
Accession number :
ejs62676060
Full Text :
https://doi.org/10.1016/j.bpsc.2023.03.009