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A General and Efficient Protocol for the Synthesis of Biaryl Ethers from Aryl Silyl Ethers Using Cs2CO3
- Source :
- Synlett; August 2004, Vol. 2004 Issue: 10 p1829-1831, 3p
- Publication Year :
- 2004
-
Abstract
- A general and efficient one-step procedure has been developed for the synthesis of biaryl ethers via direct coupling of electron-deficient arylhalides or aryl triflates to aryl t-butyldimethyl-silyl (TBS) ethers using Cs<inf>2</inf>CO<inf>3</inf>. The protocol was also applied to electron-rich arylhalides by addition of a catalytic amount of copper(I) iodide. The reaction is rapid and provides good to excellent yields.
Details
- Language :
- English
- ISSN :
- 09365214 and 14372096
- Volume :
- 2004
- Issue :
- 10
- Database :
- Supplemental Index
- Journal :
- Synlett
- Publication Type :
- Periodical
- Accession number :
- ejs6267532