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Protopanaxadiol ameliorates palmitate-induced lipotoxicity and pancreatic β-cell dysfunction in INS-1 cells

Authors :
Lee, Dahae
Choi, Sungyoul
Kang, Ki Sung
Source :
Journal of Ginseng Research; July 2023, Vol. 47 Issue: 4 p572-582, 11p
Publication Year :
2023

Abstract

Free fatty acid-induced lipotoxicity is considered to play an important role in pancreatic β-cell dysfunction. The effect of ginsenosides on palmitic acid-induced pancreatic beta-cells cell death and failure of glucose-stimulated secretion of insulin (GSIS) was evaluated in this study.

Details

Language :
English
ISSN :
12268453 and 20934947
Volume :
47
Issue :
4
Database :
Supplemental Index
Journal :
Journal of Ginseng Research
Publication Type :
Periodical
Accession number :
ejs62352050
Full Text :
https://doi.org/10.1016/j.jgr.2023.02.001