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The role of CD8+T-cell clones in immune thrombocytopenia
- Source :
- Blood; 20230101, Issue: Preprints
- Publication Year :
- 2023
-
Abstract
- •Patients with chronic ITP had clonal expansions of disease-associated TEMRA CD8+T cells.•CD8+T cells bind to platelets and cause their activation and apoptosis, defining an antibody-independent mechanism of platelet destruction.
Details
- Language :
- English
- ISSN :
- 00064971 and 15280020
- Issue :
- Preprints
- Database :
- Supplemental Index
- Journal :
- Blood
- Publication Type :
- Periodical
- Accession number :
- ejs62211850
- Full Text :
- https://doi.org/10.1182/blood.2022018380