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Alterations in platelet proteome signature and impaired platelet integrin αIIbβ3activation in patients with COVID-19

Authors :
Goudswaard, Lucy J.
Williams, Christopher M.
Khalil, Jawad
Burley, Kate L.
Hamilton, Fergus
Arnold, David
Milne, Alice
Lewis, Phil A.
Heesom, Kate J.
Mundell, Stuart J.
Davidson, Andrew D.
Poole, Alastair W.
Hers, Ingeborg
Source :
Journal of Thrombosis and Haemostasis; May 2023, Vol. 21 Issue: 5 p1307-1321, 15p
Publication Year :
2023

Abstract

Patients with COVID-19 are at increased risk of thrombosis, which is associated with altered platelet function and coagulopathy, contributing to excess mortality.

Details

Language :
English
ISSN :
15387933 and 15387836
Volume :
21
Issue :
5
Database :
Supplemental Index
Journal :
Journal of Thrombosis and Haemostasis
Publication Type :
Periodical
Accession number :
ejs62090567
Full Text :
https://doi.org/10.1016/j.jtha.2023.01.018