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Systemic inhibition and liver‐specific over‐expression of PAI‐1 failed to improve survival in all‐inclusive populations or homogenous cohorts of CLP mice

Authors :
Raeven, P.
Drechsler, S.
Weixelbaumer, K.M.
Bastelica, D.
Peiretti, F.
Klotz, A.
Jafarmadar, M.
Redl, H.
Bahrami, S.
Alessi, M.C.
Declerck, P.J.
Osuchowski, M.F.
Source :
Journal of Thrombosis and Haemostasis; June 2014, Vol. 12 Issue: 6 p958-969, 12p
Publication Year :
2014

Abstract

The role of plasminogen activator inhibitor type‐1 (PAI‐1) in abdominal sepsis remains elusive.

Details

Language :
English
ISSN :
15387933 and 15387836
Volume :
12
Issue :
6
Database :
Supplemental Index
Journal :
Journal of Thrombosis and Haemostasis
Publication Type :
Periodical
Accession number :
ejs62066816
Full Text :
https://doi.org/10.1111/jth.12565