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Cellular fibronectin promotes deep vein thrombosis in diet‐induced obese mice
- Source :
- Journal of Thrombosis and Haemostasis; March 2021, Vol. 19 Issue: 3 p814-821, 8p
- Publication Year :
- 2021
-
Abstract
- Overweight and obesity are significant risk factors for deep vein thrombosis (DVT). Cellular fibronectin containing extra domain A (Fn‐EDA), an endogenous ligand for toll‐like‐receptor 4 (TLR4), contributes to thrombo‐inflammation. The role of Fn‐EDA in the modulation of DVT is not elucidated yet.
Details
- Language :
- English
- ISSN :
- 15387933 and 15387836
- Volume :
- 19
- Issue :
- 3
- Database :
- Supplemental Index
- Journal :
- Journal of Thrombosis and Haemostasis
- Publication Type :
- Periodical
- Accession number :
- ejs62063790
- Full Text :
- https://doi.org/10.1111/jth.15206