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Evaluation of Caco-2 and human intestinal epithelial cells as in vitromodels of colonic and small intestinal integrity
- Source :
- Biochemistry and Biophysics Reports; September 2022, Vol. 31 Issue: 1
- Publication Year :
- 2022
-
Abstract
- Although the colonic cell line Caco-2 is widely used as a model of the small intestinal barrier function, it has limitations such as overestimated transepithelial electrical resistance (TEER) compared to in vivoconditions. Therefore, we investigated Human Intestinal Epithelial Cells (HIECs) as an alternative in vitromodel.
Details
- Language :
- English
- ISSN :
- 24055808
- Volume :
- 31
- Issue :
- 1
- Database :
- Supplemental Index
- Journal :
- Biochemistry and Biophysics Reports
- Publication Type :
- Periodical
- Accession number :
- ejs62023290
- Full Text :
- https://doi.org/10.1016/j.bbrep.2022.101314