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SNIFFING AROUND FOR CLINICAL SCREENING MARKERS TO PREDICT AERD IN CRSWNP PATIENTS
- Source :
- Annals of Allergy, Asthma & Immunology; November 2022, Vol. 129 Issue: 5, Number 5 Supplement 1 pS72-S72, 1p
- Publication Year :
- 2022
-
Abstract
- Aspirin-exacerbated respiratory disease(AERD) is a sub-group of chronic rhinosinusitis with nasal polyps(CRSwNP) associated with asthma and cyclooxygenase-1 inhibitor sensitivity. AERD pathogenesis involves dysregulation of arachidonic acid metabolism which favors pro-inflammatory mediator overproduction. A significant proportion of AERD patients are suspected to be undiagnosed, as aspirin sensitivity is frequently unreported. There are no standard AERD screening modalities but aspirin challenge(AC) is an effective diagnostic tool.
Details
- Language :
- English
- ISSN :
- 10811206
- Volume :
- 129
- Issue :
- 5, Number 5 Supplement 1
- Database :
- Supplemental Index
- Journal :
- Annals of Allergy, Asthma & Immunology
- Publication Type :
- Periodical
- Accession number :
- ejs61919003
- Full Text :
- https://doi.org/10.1016/j.anai.2022.08.708