Impact of EUCAST rapid antimicrobial susceptibility testing (RAST) on management of Gram-negative bloodstream infection

•Rapid antimicrobial testing (RAST) can be used routinely to rapidly detect resistant Gram-negative strains isolated from blood cultures.•RAST significantly increases the number of patients with effective antibiotic therapy on the day of positive blood culture.•RAST occasions antibiotic de-escalation on the day of positive blood culture.