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Synthesis of C4-Aminated Carbazoles and Their Derivatives via Pd/NBE Chemistry
- Source :
- The Journal of Organic Chemistry; 20230101, Issue: Preprints
- Publication Year :
- 2023
-
Abstract
- Carbazole, as one of the most important organic frameworks, has been used in optoelectronic materials and biochemistry. However, the synthesis of C4-substituted carbazole has always been an unsolved problem. This report describes the one-step synthesis of C4-aminated carbazoles and their derivatives through the series reaction of C–H amination and arylation. The substrate scope is wide. C4-Amino carbazoles substituted by C2, C6, C7, and C8 methyl groups, especially carbazole derivatives of fused rings, pyridine, and dibenzofuran, can be synthesized.
Details
- Language :
- English
- ISSN :
- 00223263
- Issue :
- Preprints
- Database :
- Supplemental Index
- Journal :
- The Journal of Organic Chemistry
- Publication Type :
- Periodical
- Accession number :
- ejs61734111
- Full Text :
- https://doi.org/10.1021/acs.joc.2c02988