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Schizophrenia Polygenic Risk During Typical Development Reflects Multiscale Cortical Organization

Authors :
Kirschner, Matthias
Paquola, Casey
Khundrakpam, Budhachandra S.
Vainik, Uku
Bhutani, Neha
Hodzic-Santor, Benazir
Georgiadis, Foivos
Al-Sharif, Noor B.
Misic, Bratislav
Bernhardt, Boris C.
Evans, Alan C.
Dagher, Alain
Source :
Biological Psychiatry Global Open Science; 20220101, Issue: Preprints
Publication Year :
2022

Abstract

Schizophrenia is widely recognized as a neurodevelopmental disorder. Abnormal cortical development in otherwise typically developing children and adolescents may be revealed using polygenic risk scores for schizophrenia (PRS-SCZ).

Details

Language :
English
ISSN :
26671743
Issue :
Preprints
Database :
Supplemental Index
Journal :
Biological Psychiatry Global Open Science
Publication Type :
Periodical
Accession number :
ejs61327032
Full Text :
https://doi.org/10.1016/j.bpsgos.2022.08.003