Back to Search Start Over

Haploidentical bone marrow transplantation in patients with relapsed or refractory severe aplastic anaemia in the USA (BMT CTN 1502): a multicentre, single-arm, phase 2 trial

Authors :
DeZern, Amy E
Eapen, Mary
Wu, Juan
Talano, Julie-An
Solh, Melhem
Dávila Saldaña, Blachy J
Karanes, Chatchada
Horwitz, Mitchell E
Mallhi, Kanwaldeep
Arai, Sally
Farhadfar, Nosha
Hexner, Elizabeth
Westervelt, Peter
Antin, Joseph H
Deeg, H Joachim
Leifer, Eric
Brodsky, Robert A
Logan, Brent R
Horowitz, Mary M
Jones, Richard J
Pulsipher, Michael A
Source :
The Lancet Haematology; September 2022, Vol. 9 Issue: 9 pe660-e669, 10p
Publication Year :
2022

Abstract

Relapsed severe aplastic anaemia is a marrow failure disorder with high morbidity and mortality. It is often treated with bone marrow transplantation at relapse post-immunosuppressive therapy, but under-represented minorities often cannot find a suitably matched donor. This study aimed to understand the 1-year overall survival in patients with relapsed or refractory severe aplastic anaemia after haploidentical bone marrow transplantation.

Details

Language :
English
ISSN :
23523026
Volume :
9
Issue :
9
Database :
Supplemental Index
Journal :
The Lancet Haematology
Publication Type :
Periodical
Accession number :
ejs61303453
Full Text :
https://doi.org/10.1016/S2352-3026(22)00206-X