Preservation of the fecal microbiome is associated with reduced severity of graft-versus-host disease

Authors :: Burgos da Silva, Marina
Ponce, Doris M.
Dai, Anqi
M. Devlin, Sean
Gomes, Antonio L. C.
Moore, Gillian
Slingerland, John
Shouval, Roni
Armijo, Gabriel K.
DeWolf, Susan
Fei, Teng
Clurman, Annelie
Fontana, Emily
Amoretti, Luigi A.
Wright, Roberta J.
Andrlova, Hana
Miltiadous, Oriana
Perales, Miguel-Angel
Taur, Ying
Peled, Jonathan U.
van den Brink, Marcel R. M.
Source :: Blood; December 2022, Vol. 140 Issue: 22 p2385-2397, 13p
Publication Year :: 2022
Abstract: •Patterns of microbial dysbiosis can be detected in fecal samples of GI aGVHD patients peri-aGVHD onset.•Markers of microbial health pre-GVHD onset are associated with longer survival and lower risk of GVHD-related mortality after allo-HCT.

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