Antioxidative Constituents from the Leaves of Hypericum styphelioides

Two new compounds have been isolated from the leaves of Hypericum styphelioides. Their structures have been established on the basis of mass spectrometry and 2D NMR techniques as 1,3,5-trihydroxy-2-(2‘,2‘-dimethyl-4‘-isopropenyl)cyclopentanylxanthone (<BO>1</BO>) and 3,5-dihydroxybenzophenon-4-β-<SCP>d</SCP>-glucoside (<BO>2</BO>). Known compounds 5-O-demethylpaxanthonin (<BO>3</BO>) and 3-geranyl-1-(3-methylbutanoyl)phloroglucinol (<BO>4</BO>) were also isolated and characterized. Compounds <BO>1</BO>−<BO>4</BO> were evaluated for their antioxidative properties in Trolox equivalent antioxidant activity (TEAC) and chemiluminescence (CL) assays.