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A sequence downstream of A-A-U-A-A-A is required for formation of simian virus 40 late mRNA 3' termini in frog oocytes.
- Source :
- Proceedings of the National Academy of Sciences of the United States of America; June 1985, Vol. 82 Issue: 12 p3949-3953, 5p
- Publication Year :
- 1985
-
Abstract
- The 3' terminus of simian virus 40 late mRNA is formed by nucleolytic cleavage of an mRNA precursor. In this report we show that efficient cleavage requires a sequence in the 3' flanking region, "downstream" of the highly conserved A-A-U-A-A-A sequence. This sequence is not required for polyadenylylation itself or for accurately positioning the 3' terminus that is formed.
Details
- Language :
- English
- ISSN :
- 00278424 and 10916490
- Volume :
- 82
- Issue :
- 12
- Database :
- Supplemental Index
- Journal :
- Proceedings of the National Academy of Sciences of the United States of America
- Publication Type :
- Periodical
- Accession number :
- ejs60454288
- Full Text :
- https://doi.org/10.1073/pnas.82.12.3949