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Human Antigen and Enzyme Markers in Man-Chinese Hamster Somatic Cell Hybrids: Evidence for Synteny Between the HL-A, PGM3, ME1, and IPO-BLoci

Authors :
Someren, H. Van
Westerveld, A.
Hagemeijer, A.
Mees, J. R.
Khan, P. Meera
Zaalberg, O. B.
Source :
Proceedings of the National Academy of Sciences of the United States of America; March 1974, Vol. 71 Issue: 3 p962-965, 4p
Publication Year :
1974

Abstract

In man-Chinese hamster somatic cell hybrids the segregation of the loci for 27 human enzyme markers and the species-specific surface antigens, including the HL-A histocompatibility antigens, was studied. The results show a synteny of the human loci for phosphoglucomutase 3, cytoplasmic malic enzyme, tetrameric indophenol oxidase, and HL-A. Furthermore, evidence is presented that the loci for the human species-specific antigens are distributed over several chromosomes.

Details

Language :
English
ISSN :
00278424 and 10916490
Volume :
71
Issue :
3
Database :
Supplemental Index
Journal :
Proceedings of the National Academy of Sciences of the United States of America
Publication Type :
Periodical
Accession number :
ejs60434537
Full Text :
https://doi.org/10.1073/pnas.71.3.962