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Interferon treatment of mice: enhanced expression of histocompatibility antigens on lymphoid cells.

Authors :
Lindahl, P
Gresser, I
Leary, P
Tovey, M
Source :
Proceedings of the National Academy of Sciences of the United States of America; April 1976, Vol. 73 Issue: 4 p1284-1287, 4p
Publication Year :
1976

Abstract

Treatment of young and mature mice with potent mouse interferon preparations results in a marked enhancement of the expression of histocompatibility antigens on the surface of thymocytes and splenic lymphocytes as measured by an enhanced absorption of alloantiserum. We postulate that such modifications of the cell surface may reflect an effect of interferon on lymphocyte maturation and may be relevant to the effect of interferon on lymphocyte function.

Details

Language :
English
ISSN :
00278424 and 10916490
Volume :
73
Issue :
4
Database :
Supplemental Index
Journal :
Proceedings of the National Academy of Sciences of the United States of America
Publication Type :
Periodical
Accession number :
ejs60427761
Full Text :
https://doi.org/10.1073/pnas.73.4.1284