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Lysyl-derived aldehydes in outer membrane proteins of Escherichia coli.
- Source :
- Proceedings of the National Academy of Sciences of the United States of America; August 1978, Vol. 75 Issue: 8 p3708-3712, 5p
- Publication Year :
- 1978
-
Abstract
- The major outer membrane proteins from Escherichia coli K-12 are modified to contain alpha-aminoadipic acid delta-semialdehyde (allysine). The allysine was found to be derived from lysine and it was identified by derivatizing it to chloronorleucine by reduction, alpha-aminoadipic acid by oxidation, and to alpha,epsilon-diaminopimelic acid by reacting it with CN- and NH3. The alpha-aminoadipic acid was identified by mass spectrometry. Two major outer membrane proteins were found to possess allysine, a modified lysine characteristically found to connective tissue.
Details
- Language :
- English
- ISSN :
- 00278424 and 10916490
- Volume :
- 75
- Issue :
- 8
- Database :
- Supplemental Index
- Journal :
- Proceedings of the National Academy of Sciences of the United States of America
- Publication Type :
- Periodical
- Accession number :
- ejs60426170
- Full Text :
- https://doi.org/10.1073/pnas.75.8.3708