Moringa concanensisNimmo. seed extracts as a potential source of bioactive molecules, antioxidants and enzyme inhibitors

Moringa concanensisNimmo (Wild Drumstick) is an underutilized edible plant used to treat various diseases. The present study was designed to investigate the phytochemical content and therapeutic potential of M. concanensisseeds using spectroscopic, chromatographic and various in-vitro assays. GC–MS analysis identified 34 compounds with palmitone, palmitic acid, oleic acid, linoleic acid, n-Pentacosane and octacosane as major constituents. Methanolic extract of seeds revealed maximum amount of phytochemicals like phenolics, flavonoids, tannins, flavanols, proanthocyanins and vitamin E. Similarly, methanolic extract showed moderate α-amylase inhibitory effect (72.81 ± 0.46 µg/mL), and ethyl acetate extract revealed notable α-glucosidase inhibitory effect (IC50of 40.80 ± 0.53 µg/mL). All the studied extracts exhibited decent free radical scavenging ability. Chloroform and ethyl acetate extract of seeds displayed the lowest MIC against the growth of Bacillus subtilis(59.37 µg/mL). The study results support the possible use of M. concanensisseeds towards the preparation of therapeutic and food formulations.