Abstract 12619: Long-term Clinical Outcomes of Long Coronary Lesions in Acute Myocardial Infarction Patients Underwent Percutaneous Coronary Intervention

Background:Lesion length had been investigated widely as a strong predictor of low procedural complications, high complication rate and high restenosis rate after percutaneous coronary intervention (PCI). However, there are limited data regarding the long-term clinical outcomes following successful PCI for long lesions in the setting of acute myocardial infarction (AMI).Methods:A total 1302 AMI patients underwent PCI were enrolled. Patients were divided into two groups; 1) long lesion group (?30mm, N=737) and 2) short lesion group (<30mm, N=565).Individual and composite major clinical outcomes including major adverse cardiac events (MACE), the composite of total death, myocardial infarction (MI), repeat revascularization and stent thrombosis were compared between the two groups up to 5 years.Results:At 5 years follow up, long lesion group had significantly higher incidence revascularization (HR: 1.377, 95% CI: 1.030 to 1.840; p = 0.031) including target lesion revascularization (TLR, HR: 1.620, 95% CI: 1.137 to 2.308; p = 0.008) and MACE (HR: 1.338, 95% CI: 1.062 to 1.685; p = 0.014) than short lesion group (Table). Using multivariate logistic regression, and after adjusting for potential risk factors, long coronary lesion patients had higher incidence of MACE including total death, cardiac death, revascularization and stent thrombosis up to 5 years.Conclusion:In this study, long coronary lesions (?30mm) treated with drug-eluting stents after AMI were associated with higher incidence of revascularization and total MACE than short coronary lesion (< 30 mm) up to 5 years.