Abstract 10136: A Multicenter Analysis of Reintervention After Balloon Valvuloplasty for Critical Pulmonary Valve Stenosis

Introduction:Reintervention rate after percutaneous balloon valvuloplasty (BV) for critical congenital pulmonary valve stenosis (PS) is unknown.Hypothesis:Repeat BV or surgical intervention within 1 year of BV for critical PS is uncommon.Methods:The Pediatric Health Information Systems database was queried for patients admitted at ?3 days of age from 2004-2018 with a principal diagnosis of PS who received prostaglandin and underwent primary BV. Study data included demographic variables, resource utilization (e.g. length of stay, ECMO use, etc), and reintervention during either the index hospitalization or a subsequent readmission to the index hospital within 1 year. Freedom from reintervention or death was assessed with Kaplan-Meier analysis, and risk factors were examined with multivariate analysis.Results:Balloon valvuloplasty was the principal procedure for critical PS in 1014 patients (53% male) from 49 hospitals (Table). Reintervention occurred in 4.6% (47/1014) during the index hospitalization (32 BV and 15 operative). On readmission, 44 patients (4.3%) underwent reintervention at a median of 81 (IQR: 54,144) days after initial BV. Among patients with reintervention during the index hospitalization, 17% (8/47) also underwent reintervention during a readmission. In-hospital mortality was 1.3% during the study. Freedom from death or reintervention was 91% at 1-year. Male sex was the only risk factor predictive of reintervention (OR: 2.1; 95% CI: 1.2-3.5; p=0.009).Conclusions:Reintervention for critical PS was not uncommon at 1-year in this large, retrospective multicenter study. Male sex is associated with increased rate of reintervention.