Chemical constituents from Hibiscus hamaboand their antiphotoaging effects on UVA‐induced CCD‐986sk

To investigate the phytochemical constituents of Hibiscus hamabo, a chromatographic method was used. A new phenolic glucoside, woodorien A (1), along with 10 known compounds, rutin (2), isoquercetin (3), nicotiflorin (4), astragalin (5), trans‐tiliroside (6), N‐trans‐feruloyltyramine (7), N‐trans‐caffeoyltyramine (8), woodorien (9), quercetin 3′‐galactopyranoside (10), and cis‐tiliroside (11), was isolated. The structure of 1was identified as ethyl 3‐O‐β‐d‐glucopyranosyl‐4‐hydroxybenzoate. Compounds 8, 9, and 11were isolated from genus Hibiscus, and 2–7and 10were isolated from H. hamabofor the first time. Their chemical structures were determined through the interpretation of spectroscopic data. The properties of the UVA photoaging induction assay of all isolated compounds were measured. Compounds 3, 8, and 10exhibited recovery from photoaging induced by UVA in CCD‐986sk. These results suggest that H. hamabois a potential source of natural antiphotoaging ingredients and can be used in cosmetic applications. A new compound, woodorien A (1), together with 10 known compounds (2–11) was isolated from Hibiscus hamabovia chromatography. Their chemical structures were elucidated on the basis of spectroscopic methods. Among these, compounds 8, 9, and 11were reported from genus Hibiscus, and 2–7and 10were reported from H. hamabofor the first time. All isolated compounds 1–11were tested by a UVA photoaging induction assay. As a result, isoquercetin (3), N‐trans‐caffeoyltyramine (8), and quercetin 3′‐galactopyranoside (10) showed strong antiphotoaging activity.