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Complement gene variant effect on relapse of complement-mediated thrombotic microangiopathy after eculizumab cessation
- Source :
- Blood Advances; February 2023, Vol. 7 Issue: 3 p340-350, 11p
- Publication Year :
- 2023
-
Abstract
- •In CM-TMA, variants in specific genes/regions are associated with high risk of relapse after eculizumab is discontinued.•In CM-TMA, eculizumab discontinuation is appropriate in patients with a low risk of relapse.
Details
- Language :
- English
- ISSN :
- 24739529 and 24739537
- Volume :
- 7
- Issue :
- 3
- Database :
- Supplemental Index
- Journal :
- Blood Advances
- Publication Type :
- Periodical
- Accession number :
- ejs59637794
- Full Text :
- https://doi.org/10.1182/bloodadvances.2021006416