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High-Dose Osimertinib for CNS progression in EGFR+ NSCLC: A Multi-Institutional Experience

Authors :
Piper-Vallillo, A.J.
Rotow, Julia K.
Aredo, Jacqueline V.
Shaverdashvili, Khvaramze
Jia, Luo
Carlisle, Jennifer
Husain, Hatim
Muzikansky, Alona
Heist, Rebecca
Rangachari, Deepa
Ramalingam, Suresh S.
Wakelee, Heather A.
Yu, Helena A.
Sequist, Lecia
Bauml, Joshua M.
Neal, Joel W.
Piotrowska, Zofia
Source :
JTO Clinical and Research Reports; 20220101, Issue: Preprints
Publication Year :
2022

Abstract

This multicenter review evaluated the efficacy and safety of osimertinib dose-escalation for CNS progression developing on osimertinib 80 mg in EGFR-mutant NSCLC.

Details

Language :
English
ISSN :
26663643
Issue :
Preprints
Database :
Supplemental Index
Journal :
JTO Clinical and Research Reports
Publication Type :
Periodical
Accession number :
ejs59490371
Full Text :
https://doi.org/10.1016/j.jtocrr.2022.100328