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Making innate sense of mRNA vaccine adjuvanticity
- Source :
- Nature Immunology; April 2022, Vol. 23 Issue: 4 p474-476, 3p
- Publication Year :
- 2022
-
Abstract
- mRNA vaccines such as those used to prevent COVID-19 owe part of their success to methylation that masks immunostimulatory properties of the mRNA, but the immunological mechanisms of adjuvanticity are unclear. Two new studies reveal distinct mechanisms for innate sensing of this hidden adjuvant.
Details
- Language :
- English
- ISSN :
- 15292908 and 15292916
- Volume :
- 23
- Issue :
- 4
- Database :
- Supplemental Index
- Journal :
- Nature Immunology
- Publication Type :
- Periodical
- Accession number :
- ejs59320910
- Full Text :
- https://doi.org/10.1038/s41590-022-01168-4