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Abnormal maximal and submaximal cardiopulmonary exercise capacity in pediatric stem cell transplant recipients despite normal standard echocardiographic parameters: a pilot study

Authors :
Powell, Adam W.
Urbina, Elaine M.
Madueme, Peace
Rotz, Seth
Chin, Clifford
Taylor, Michael D.
Mays, Wayne A.
Davies, Stella M.
Lane, Adam
Berger, Suzanne
Jodele, Sonata
Dandoy, Christopher E.
Ryan, Thomas D.
Source :
Transplantation and Cellular Therapy; 20220101, Issue: Preprints
Publication Year :
2022

Abstract

•Cardiac dysfunction is a feared complication following stem cell transplantation•Subclinical vascular and cardiac disease have been minimally studied•Patients following stem cell transplantation tend to have abnormal exercise capacity despite having normal vascular, pulmonary, and cardiac function•Exercise parameters tend to be abnormal throughout exercise, meaning submaximal effort exercise testing can provide helpful information in the event the patient is unable to complete a full effort test

Details

Language :
English
ISSN :
26666375 and 26666367
Issue :
Preprints
Database :
Supplemental Index
Journal :
Transplantation and Cellular Therapy
Publication Type :
Periodical
Accession number :
ejs59020790
Full Text :
https://doi.org/10.1016/j.jtct.2022.02.019