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The Intraoperative Microlesion Effect Positively Correlates With the Short-Term Clinical Effect of Deep Brain Stimulation in Parkinson's Disease

Authors :
Lange, Stèfan F.
Kremer, Naomi I.
van Laar, Teus
Lange, Fiete
Steendam-Oldekamp, T. Elien
Oterdoom, D. L. Marinus
Absalom, Anthony R.
van Dijk, J. Marc C.
Drost, Gea
Source :
Neuromodulation: Technology at the Neural Interface; February 2023, Vol. 26 Issue: 2 p459-465, 7p
Publication Year :
2023

Abstract

During the surgical procedure of deep brain stimulation (DBS), insertion of an electrode in the subthalamic nucleus (STN) frequently causes a temporary improvement of motor symptoms, known as the microlesion effect (MLE). The objective of this study was to determine the correlation between the intraoperative MLE and the clinical effect of DBS.

Details

Language :
English
ISSN :
10947159 and 15251403
Volume :
26
Issue :
2
Database :
Supplemental Index
Journal :
Neuromodulation: Technology at the Neural Interface
Publication Type :
Periodical
Accession number :
ejs58936285
Full Text :
https://doi.org/10.1111/ner.13523