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Chemoenzymatic one-pot reaction from carboxylic acid to nitrile viaoximeElectronic supplementary information (ESI) available. See DOI: 10.1039/d1cy01694f
- Source :
- Catalysis Science & Technology; 2022, Vol. 12 Issue: 1 p62-66, 5p
- Publication Year :
- 2022
-
Abstract
- We report a new chemoenzymatic cascade starting with aldehyde synthesis by carboxylic acid reductase (CAR) followed by chemical in situoxime formation. The final step to the nitrile is catalyzed by aldoxime dehydratase (Oxd). Full conversions of phenylacetic acid and hexanoic acid were achieved in a two-phase mode.
Details
- Language :
- English
- ISSN :
- 20444753 and 20444761
- Volume :
- 12
- Issue :
- 1
- Database :
- Supplemental Index
- Journal :
- Catalysis Science & Technology
- Publication Type :
- Periodical
- Accession number :
- ejs58621883
- Full Text :
- https://doi.org/10.1039/d1cy01694f