Genomic characterisation of Escherichia coliisolates co-producing NDM-5 and OXA-1 from hospitalised patients with invasive infections

•Carbapenemase-producing Enterobacteriaceae represent a public-health concern owing to limited therapeutic options.•Three E. coliisolates of ST44, ST405 and ST167 defined as high-risk clones owing to their multidrug-resistant profile.•It is important to monitor the spread of these strains co-harbouring different carbapenemases.•This is especially important in the hospital environment to avoid therapeutic failure.