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Common Gene Expression Signature of B-Cells of WaldenströmMacroglobulinemia (WM) and IgM Monoclonal Gammopathies of Undetermined Significance (IgM MGUS) Compared to Healthy Subjects

Authors :
Trojani, Alessandra
Di Camillo, Barbara
Bossi, Luca Emanuele
Greco, Antonino
Leuzzi, Livia
Tedeschi, Alessandra
Frustaci, Anna Maria
Deodato, Marina
Zamprogna, Giulia
Melluso, Agostina
Panzeri, Alessia
Montillo, Marco
Beghini, Alessandro
Cairoli, Roberto
Source :
Blood; November 2021, Vol. 138 Issue: 1, Number 1 Supplement 1 p4317-4317, 1p
Publication Year :
2021

Abstract

We performed a comparative gene expression profiling (GEP) study on B-cells and plasma cells of WaldenströmMacroglobulinemia (WM), IgM monoclonal gammopathies of undetermined significance (IgMMGUS), and normal individuals (CTRLs) to identify GEP changes as reliable predictors of progression of IgMMGUS to WM.

Details

Language :
English
ISSN :
00064971 and 15280020
Volume :
138
Issue :
1, Number 1 Supplement 1
Database :
Supplemental Index
Journal :
Blood
Publication Type :
Periodical
Accession number :
ejs58547361
Full Text :
https://doi.org/10.1182/blood-2021-147712