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A Single-Arm, Open-Label, Pilot Study of the JAK1 Selective Inhibitor Itacitinib for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome in T-Cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation

Authors :
Abboud, Ramzi
Gao, Feng
Rettig, Michael P.
Eisele, Jeremy
Gehrs, Leah
Wallace, Nichols
Abboud, Camille
Westervelt, Peter
Uy, Geoffrey L.
Cashen, Amanda F.
Christopher, Matt
Ghobadi, Armin
Jacoby, Meagan A.
Pusic, Iskra
Stockerl-Goldstein, Keith E.
DiPersio, John F.
Schroeder, Mark A.
Source :
Blood; November 2021, Vol. 138 Issue: Supplement 1 p100-100, 1p
Publication Year :
2021

Abstract

Uy: Astellas: Honoraria, Speakers Bureau; Novartis: Consultancy; Agios: Consultancy; Jazz: Consultancy; Genentech: Consultancy; AbbVie: Consultancy; GlaxoSmithKline: Consultancy; Macrogenics: Research Funding. Ghobadi: Atara: Consultancy; Amgen: Consultancy, Research Funding; Wugen: Consultancy; Celgene: Consultancy; Kite, a Gilead Company: Consultancy, Honoraria, Research Funding. Jacoby: Abbvie: Research Funding; Jazz: Research Funding. Pusic: Syndax: Other: Advisory Board. Schroeder: Equillium Inc: Honoraria; Janssen: Honoraria; Sanofi Genzyme: Honoraria.

Details

Language :
English
ISSN :
00064971 and 15280020
Volume :
138
Issue :
Supplement 1
Database :
Supplemental Index
Journal :
Blood
Publication Type :
Periodical
Accession number :
ejs58317000
Full Text :
https://doi.org/10.1182/blood-2021-144591