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Application of Fourier transform infrared spectroscopy spectroscopy for real-time typing of Acinetobacter baumanniioutbreak in intensive care unit
- Source :
- Future Microbiology; 20210101, Issue: Preprints
- Publication Year :
- 2021
-
Abstract
- Aim:Acinetobacter baumanniiis a pathogen of serious concern, often exhibiting multiple antibiotic resistance, frequently associated with hospital outbreaks in intensive care units. A prompt detection and tracking of these isolates is crucial. Reference methods for typing (pulsed-field gel electrophoresis, whole-genome sequencing) are accurate, but expensive and time-consuming, therefore limited to retrospective analysis. Materials & methods:In this study, the application of the FTIR-based IR Biotyper®(IRBT) to track and monitor in real time the spread of a multidrug-resistant A. baumanniioutbreak was investigated. The index case and the multidrug-resistant A. baumanniiisolates collected in the following 3 weeks were investigated. Results:IR Biotyper®clustering results were fully confirmed by pulsed-field gel electrophoresis results. Conclusions:IR Biotyper represent a promising tool for real-time hospital hygiene, enabling a prompt and reliable typing.
Details
- Language :
- English
- ISSN :
- 17460913 and 17460921
- Issue :
- Preprints
- Database :
- Supplemental Index
- Journal :
- Future Microbiology
- Publication Type :
- Periodical
- Accession number :
- ejs58101952
- Full Text :
- https://doi.org/10.2217/fmb-2020-0276