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Genome of Sindbis Virus
- Source :
- The Journal of Virology; January 1972, Vol. 9 Issue: 1 p102-109, 8p
- Publication Year :
- 1972
-
Abstract
- 32P-labeled ribonucleic acid (RNA) from purified Sindbis virus was examined for the presence of hidden breaks. Viral RNA was treated with acid at pH 2.9 or with formaldehyde and was analyzed on sucrose gradients or by polyacrylamide gel electrophoresis. The sedimentation pattern and mobility on polyacrylamide gels of the 42SRNA was unaffected by heating and quick cooling and was not altered by denaturing agents such as dimethyl sulfoxide and urea. No evidence that Sindbis RNA is a polyaggregate of fragments was obtained. It is concluded that the genome consists of a continuous length of single-stranded polynucleotide.
Details
- Language :
- English
- ISSN :
- 0022538X and 10985514
- Volume :
- 9
- Issue :
- 1
- Database :
- Supplemental Index
- Journal :
- The Journal of Virology
- Publication Type :
- Periodical
- Accession number :
- ejs57815587
- Full Text :
- https://doi.org/10.1128/jvi.9.1.102-109.1972