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Occurrence of the p019Gene in the blaKPC-Harboring Plasmids: Adverse Clinical Impact for Direct Tracking of KPC-Producing Klebsiella pneumoniaeby Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry

Authors :
Gato, Eva
Constanso, Ignacio Pedro
Rodiño-Janeiro, Bruno Kotska
Guijarro-Sánchez, Paula
Alioto, Tyler
Arroyo, Manuel Jesús
Méndez, Gema
Mancera, Luis
Gut, Marta
Gut, Ivo
Álvarez-Tejado, Miguel
Bou, Germán
Oviaño, Marina
Source :
Journal of Clinical Microbiology; May 2021, Vol. 59 Issue: 8
Publication Year :
2021

Abstract

Matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) has recently been used for the direct detection of KPC-producing isolates by analysis of the 11,109 Da mass peak representing the P019 protein. In this study, we evaluate the presence of the 11,109?Da mass peak in a collection of 435 unduplicated Klebsiella pneumoniaeclinical isolates.

Details

Language :
English
ISSN :
00951137 and 1098660X
Volume :
59
Issue :
8
Database :
Supplemental Index
Journal :
Journal of Clinical Microbiology
Publication Type :
Periodical
Accession number :
ejs57792926
Full Text :
https://doi.org/10.1128/JCM.00238-21