Genetic Polymorphisms Influence Plasmodium ovalePCR Detection Accuracy

ABSTRACTDetection of Plasmodium ovaleby use of a nested PCR assay with a novel Plasmodium ovaleprimer set was superior to detection of Plasmodium ovaleby real-time PCR assays. Nested PCR was also better at detecting P. malariae. The detection of P. ovalein many patients first admitted >2 months following their return to Italy indicated that P. ovalerelapses are common.