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Protective effect of monoclonal antibodies on lethal mouse hepatitis virus infection in mice
- Source :
- The Journal of Virology; July 1986, Vol. 59 Issue: 1 p168-171, 4p
- Publication Year :
- 1986
-
Abstract
- Neutralizing and nonneutralizing monoclonal antibodies to the peplomer glycoprotein and nucleocapsid protein of a mouse hepatitis virus (MHV), MHV-NuU, protected mice against lethal MHV-2 challenge. Histopathologically, livers of mice receiving protective antibodies showed some focal necrotic lesions with remarkable cellular infiltration instead of fulminant hepatitis caused by MHV-2.
Details
- Language :
- English
- ISSN :
- 0022538X and 10985514
- Volume :
- 59
- Issue :
- 1
- Database :
- Supplemental Index
- Journal :
- The Journal of Virology
- Publication Type :
- Periodical
- Accession number :
- ejs57746579
- Full Text :
- https://doi.org/10.1128/jvi.59.1.168-171.1986