Back to Search Start Over

Some properties of subunits of DNA gyrase from Pseudomonas aeruginosa PAO1 and its nalidixic acid-resistant mutant

Authors :
Inoue, Y
Sato, K
Fujii, T
Hirai, K
Inoue, M
Iyobe, S
Mitsuhashi, S
Source :
Journal of Bacteriology; May 1987, Vol. 169 Issue: 5 p2322-2325, 4p
Publication Year :
1987

Abstract

Subunits A and B of DNA gyrase were purified from Pseudomonas aeruginosa PAO1 and its mutant, which was resistant to nalidixic acid. Inhibition tests of DNA gyrases reconstituted with a combination of subunits from the two strains showed that an alteration of subunit A but not subunit B caused bacteria to resist fluoroquinolones.

Details

Language :
English
ISSN :
00219193 and 10985530
Volume :
169
Issue :
5
Database :
Supplemental Index
Journal :
Journal of Bacteriology
Publication Type :
Periodical
Accession number :
ejs57611681
Full Text :
https://doi.org/10.1128/jb.169.5.2322-2325.1987